Welcome
Emergency medicine clinical research is vital to improving the acute management of disease and injury and providing a healthcare safety-net for our community. In his lab, Andrew Meltzer, MD, is dedicated to translating novel diagnostic strategies and treatments into clinical practice. The lab focuses on innovative point-of-care diagnostics with a focus on common emergency phenotypes. In the fast-paced emergency setting, the use of rapid diagnostics speeds definitive care, lessens wait times, and can improve resource allocation. Research in emergency management of infectious diseases is essential for tackling emerging pathogens and antibiotic resistance. Abdominal pain, a common yet challenging symptom, requires focused studies for accurate diagnosis and effective treatment. This research not only strengthens the scientific foundation of emergency medicine but also directly contributes to saving lives and mitigating urgent health threats.
The lab aims to translate technology from bench to bedside. Ongoing studies focus on novel biomarkers of bacterial infection, modifiable risk factors for substance use disorders, reducing recidivism for chronic abdominal pain and developing machine-learning algorithms to reduce crowding and boarding. Prior work includes serving as principal investigator on an NIH-funded multi-center randomized control trial on medical expulsive therapy for renal colic.
In recent years, Andrew Meltzer, MD, has served as PI for:
- multi-center trial examining novel ways to diagnose gastrointestinal hemorrhage,
- a prospective observational study on recurrent abdominal pain and
- a randomized control trial comparing different modes of ventilation for ED patients with respiratory distress.
In addition, the lab is an original site for the CDC-funded Recover grant and the CDC Resp-Lens surveillance program for respiratory infectious diseases. The lab has recently completed studies using syndromic surveillance in the ED for infectious diseases and a randomized control trial of novel potassium binders in hyperkalemic patients.
As part of a team of experts, Andrew Meltzer, MD, has developed guidelines for the care of abdominal pain in the ED in addition to international guidelines for the acute management of gastrointestinal bleeding. His clinical experience includes community, academic and military hospitals ensuring that his research has a real-world application.
The lab is funded by NIH, CDC and private partners ranging from established industry leaders to innovative start-ups. Andrew Meltzer, MD, has had over 100 authorships and an h-index of 21.